Prime Minister David Cameron's first major government reshuffle is coming together.

Jeremy Hunt's moved from Culture to become the new Health Secretary - as Andrew Lansley's named Leader of the House of Commons.

Patrick McLoughlin, formerly chief whip, will replace Justine Greening as Transport Secretary.

While Chris Grayling is the new Justice Secretary - with Ken Clarke staying on as a minister without portfolio ... which he's denied is a humiliation:

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Chancellor George Osborne and Education Secretary Michael Gove keep their roles.